Abdool Karim, is an infectious diseases epidemiologist whose seminal contributions spanning over three decades have shaped the global HIV prevention landscape, notably in prevention technologies for women. She demonstrated that ARVs prevent sexually transmitted HIV that laid the foundation for HIV pre-exposure prophylaxis (PrEP); and has provided insights in Africa and globally on the impact of Covid-19 on HIV and in the evaluation of Covid-19 vaccines and therapeutics. Abdool Karim is the President of the World Academy of Sciences (TWAS). She is an elected member of the National Academy of Medicine (USA); and Fellow of The World Academy of Science, Royal Society of South Africa, Academy of Science of South Africa and the African Academy of Science. Her research contributions have been recognized nationally and internationally with over 30 honors including South Africa’s Order of Mapungubwe, 2014 TWAS-Lenovo Prize; the John Dirks Canada Gairdner Global Health Award; the 2020 Christophe Mérieux Prize; and the 4th Hideyo Noguchi Africa Prize for Medical Research. She is the Associate Scientific Director of CAPRISA; Professor in Clinical Epidemiology, Columbia University; and Pro-Vice Chancellor for African Health, University of KwaZulu-Natal, South Africa.